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KMID : 0377619710210040305
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Korean Jungang Medical Journal
1971 Volume.21 No. 4 p.305 ~ p.308
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Sensitivity of Minocycline of Enterobacteriaceae carrying R factors
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Abstract
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For the examination of the sensitivity to minocycline (MIND) of Enterobacteriaceae isolated in Korea, a total of 278 strains of organism, including 80 strains of Escherichia coli, 110 strains of Shigella, and 88 strains of Salmonella, was employed.
Among 278 isolates, 267 strains (96. 1 /o) were sensitive to MINO, while 2 strains of E. coli, 4 strains of Shigella and 5 strains of Salmonella were found to be resistant to MINO.
Among 118 strains carrying R factors which contain markers for a variety of drug resistances, including tetracycline resistance, 7 strains(5.9%) were resistant to MINO. Among 70 strains of tetracycline-resistant bacteria, 7 strains(10%) were resistant to MINO, showing that the organisms isolated in Korea, such as E. coli, Shigella, and Salmonella, are more susceptible in vitro to MINO than to tetracycline.
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